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About Deep Piction

Deep Piction is a pioneering biotechnology firm located in Munich specializing in cutting-edge tissue clearing, 3D imaging, spatial biology, and AI technologies that aid in expediting drug discovery and therapeutic innovation. Their work integrates whole-organ and whole-body imaging at single-cell resolution alongside quantitative image analysis, spatial molecular profiling, and artificial intelligence. These technologies support internal drug development projects and collaborations with pharmaceutical and biotech partners.

Role Overview

This hands-on scientific position focuses on driving and enabling projects to develop, standardize, and expand workflows related to tissue clearing, light-sheet microscopy, and quantitative image analysis. The candidate will manage tissue-clearing and 3D imaging assignments, collaborate closely with experimental, computational, and commercial teams, and transform complex biological specimens into robust quantitative data.

Key Responsibilities

Lead tissue clearing and 3D imaging projects supporting internal research and external partnerships.
Design and perform whole-organ and whole-body tissue clearing, staining, imaging, and analytical protocols.
Operate and enhance light-sheet microscopy processes and infrastructure.
Assist in quantitative image analysis, visualization, atlas alignment, and biological data interpretation.
Collaborate with AI specialists to create scalable image-analysis pipelines and automation solutions.
Refine protocols, quality control measures, documentation, reproducibility, and throughput capabilities.
Coordinate cross-functional projects involving experimental, imaging, AI, and therapeutic development teams.
Train and mentor junior researchers and technical personnel.
Participate in authoring scientific reports, presentations, publications, patents, and technology development activities.
Optionally assist with animal study planning and compliances.

Qualifications and Experience

Master's or PhD in life sciences, biomedical engineering, optical physics, neuroscience, bioengineering, or related disciplines.
Proven experience in tissue clearing, fluorescence microscopy, 3D histology, or whole-mount imaging techniques.
Practical expertise in light-sheet microscopy and large-volume biological image acquisition.
Familiarity with Imaris and/or arivis Vision4D software.
Knowledge of BigStitcher or similar tools for data stitching and processing of large datasets.
Competence in atlas registration, cell detection, segmentation, and quantitative analysis of cleared tissue samples.
Strong independent planning, execution, troubleshooting, and documentation skills for complex experiments.
Excellent organizational skills to manage multiple projects and collaborations simultaneously.
Fluent in scientific English with effective communication skills across experimental and computational teams.

Preferred Additional Skills

Experience with Fiji/ImageJ, Python-based image processing, napari visualization, automation, or batch processing pipelines.
Background in machine learning or deep learning for image analysis.
Expertise in whole-organ or whole-body imaging datasets.
Knowledge of antibody labeling, whole-mount immunostaining, tissue expansion, or spatial molecular profiling.
Experience with quality assurance, protocol standardization, or working in biotech/pharmaceutical environments.
FELASA B certification, animal study coordination, or regulatory documentation experience.
Use of VR-based annotation or 3D proofreading tools.
Supervision of students, technicians, or junior researchers.

Employment Details and Benefits

Access to advanced technologies in tissue clearing, whole-body imaging, and AI.
Work with unique 3D cellular-resolution datasets spanning various therapeutic areas.
Direct involvement in pharmaceutical collaborations and internal drug development initiatives.
Collaborate with interdisciplinary teams across biology, imaging, AI, data science, and business development.
Opportunity to influence and scale pivotal scientific workflows in a growing biotech company.
Dynamic, international, and interdisciplinary work environment based in Munich.
Full-time, onsite role with competitive salary reflecting experience and qualifications.
Flexible starting date, ideally as soon as possible.

Application Guidelines

Submit a singular PDF file combining your CV, a cover letter, and a detailed summary of relevant experience in tissue clearing, light-sheet microscopy, 3D image analysis, and project management.
Do not send additional supporting documents (certificates, references, letters, publications) at this initial stage.
Your application will be reviewed on a rolling basis until the vacancy is filled.

Scientist - Tissue Clearing and 3D Image Analysis