Fractional COO (Part-Time)

Role overview

An innovative biotechnology business focused on next-generation biomarker discovery and precision health is looking for a fractional Chief Operating Officer to help guide growth and tighten execution. The position works alongside senior leadership to create scalable operating systems, advance company-wide initiatives, and support expansion across the U.S. life sciences sector.

Compensation

The engagement is paid at $185 per hour.

Responsibilities

• Work closely with the CEO and leadership group to shape and carry out growth plans.
• Design and improve operating processes across scientific, business, and administrative areas.
• Lead cross-functional workstreams that improve efficiency and support scale.
• Contribute to budgeting, financial planning, resource planning, and operational projections.
• Create, track, and review KPIs and other operating metrics.
• Support fundraising efforts, investor updates, and strategic partnership discussions.
• Coordinate with outside stakeholders such as research partners, vendors, consultants, and business collaborators.
• Oversee project management activities so goals, deliverables, and timelines stay aligned.
• Assess and put in place the systems, policies, and infrastructure needed for expansion.
• Offer operational leadership and guidance on organizational development and best practices.

Requirements

• Background as a COO, VP of Operations, General Manager, or in a comparable executive role.
• Experience in biotechnology, life sciences, healthcare technology, diagnostics, or a related field is strongly preferred.
• Proven ability to help early-stage or growth-stage organizations move forward.
• Solid understanding of operations, strategic planning, budgeting, and organizational design.
• Experience engaging with investors, boards, and external strategic partners.
• Strong leadership, communication, and stakeholder-management abilities.
• Comfort working in both strategic and hands-on modes in a fast-moving environment.
• MBA, advanced scientific degree, or equivalent practical experience is preferred.
• Additional preferred background includes commercialization of biotech, diagnostics, or healthcare innovation platforms.
• Familiarity with research partnerships, technology alliances, and regulated healthcare settings is preferred.
• Experience scaling startup operations and building core organizational infrastructure is an advantage.

Work arrangement

This is a part-time fractional contract role based in Cambridge, MA, with a hybrid setup.

Additional information

The role supports strategic growth, operational execution, fundraising coordination, and the development of scalable internal systems for a biotechnology company operating in the precision health space.